The purpose of this LSU NCBRT presentation is to explain the different types of biological incidents. Emergency responders, law enforcement, and public health officials should be aware of the implications and consequences of biological incidents—whether natural, accidental, or intentional. Law enforcement plays a critical role and should be involved early in a response to a biological incident so that critical evidence is not lost in the event that a crime has been committed. Understanding these incidents enables a comprehensive and effective response, highlighting the importance of cooperation among various agencies to safeguard public health and security.